This can sometimes be overwhelming and frankly annoying. Many of the photos or posts I comment on are just 'one-offs' for me - I don't need to see who else liked them or commented on them, and I certainly don't want to be notified every time they do. Sound familiar?
Here's what you do:
1) Click on the notification that is informing you of someone else's interaction with a friend's post. For example: 'Jamie Good likes your comment....' This will take you to where you originally commented or 'liked'.
2) See 3 choices-as shown in the image below: Like, Comment, Unfollow post.